SARS-COV-2 protein NSP9 promotes cytokine production by targeting TBK1

SARS-COV-2 infection-induced excessive or uncontrolled cytokine storm may cause injury of host tissue or even death. However, the mechanism by which SARS-COV-2 causes the cytokine storm is unknown. Here, we demonstrated that SARS-COV-2 protein NSP9 promoted cytokine production by interacting with an...

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Bibliographic Details
Main Authors: Yihua Zhang, Bowen Xin, Yinan Liu, Wenyi Jiang, Wendong Han, Jian Deng, Peihui Wang, Xiaowu Hong, Dapeng Yan
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-10-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1211816/full