Analysis the Effectiveness of Remdesivir, Galidesivir, Sofosbuvir, Tenofovir and Ribavirin as Potential Therapeutic Drug target against SARS-Cov-2 RNA-Dependent RNA Polymerase (RdRp): An in Silico Docking Study
Background & Aims: The active site of RdRp-CoV is highly conserved, with two successive and surface-accessible aspartates in a beta-turn structure. Antiviral drugs Remdesivir, Galidesivir, Tenofovir, Sofosbuvir, and Ribavirin are known as inhibitors of RdRps, while lopinavir and rotinavir are k...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Urmia University of Medical Sciences
2023-07-01
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| Series: | Journal of Research in Applied and Basic Medical Sciences |
| Subjects: | |
| Online Access: | http://ijrabms.umsu.ac.ir/article-1-261-en.pdf |