Analysis the Effectiveness of Remdesivir, Galidesivir, Sofosbuvir, Tenofovir and Ribavirin as Potential Therapeutic Drug target against SARS-Cov-2 RNA-Dependent RNA Polymerase (RdRp): An in Silico Docking Study
Background & Aims: The active site of RdRp-CoV is highly conserved, with two successive and surface-accessible aspartates in a beta-turn structure. Antiviral drugs Remdesivir, Galidesivir, Tenofovir, Sofosbuvir, and Ribavirin are known as inhibitors of RdRps, while lopinavir and rotinavir are k...
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| Format: | Artikel |
| Sprache: | English |
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Urmia University of Medical Sciences
2023-07-01
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| Schriftenreihe: | Journal of Research in Applied and Basic Medical Sciences |
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| Online Zugang: | http://ijrabms.umsu.ac.ir/article-1-261-en.pdf |