Analysis the Effectiveness of Remdesivir, Galidesivir, Sofosbuvir, Tenofovir and Ribavirin as Potential Therapeutic Drug target against SARS-Cov-2 RNA-Dependent RNA Polymerase (RdRp): An in Silico Docking Study

Analysis the Effectiveness of Remdesivir, Galidesivir, Sofosbuvir, Tenofovir and Ribavirin as Potential Therapeutic Drug target against SARS-Cov-2 RNA-Dependent RNA Polymerase (RdRp): An in Silico Docking Study

Background & Aims:  The active site of RdRp-CoV is highly conserved, with two successive and surface-accessible aspartates in a beta-turn structure. Antiviral drugs Remdesivir, Galidesivir, Tenofovir, Sofosbuvir, and Ribavirin are known as inhibitors of RdRps, while lopinavir and rotinavir are k...

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Detalles Bibliográficos
Main Authors: Rajneesh Prajapat, Suman Jain
Formato: Artigo
Idioma:English
Publicado: Urmia University of Medical Sciences 2023-07-01
Series:Journal of Research in Applied and Basic Medical Sciences
Subjects:
antiviral drugs
fda
in silico
remdesivir
rdrp
sars-cov-2
Acceso en liña:http://ijrabms.umsu.ac.ir/article-1-261-en.pdf

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