Analysis the Effectiveness of Remdesivir, Galidesivir, Sofosbuvir, Tenofovir and Ribavirin as Potential Therapeutic Drug target against SARS-Cov-2 RNA-Dependent RNA Polymerase (RdRp): An in Silico Docking Study

Background & Aims:  The active site of RdRp-CoV is highly conserved, with two successive and surface-accessible aspartates in a beta-turn structure. Antiviral drugs Remdesivir, Galidesivir, Tenofovir, Sofosbuvir, and Ribavirin are known as inhibitors of RdRps, while lopinavir and rotinavir are k...

詳細記述

書誌詳細
主要な著者: Rajneesh Prajapat, Suman Jain
フォーマット: 論文
言語:English
出版事項: Urmia University of Medical Sciences 2023-07-01
シリーズ:Journal of Research in Applied and Basic Medical Sciences
主題:
オンライン・アクセス:http://ijrabms.umsu.ac.ir/article-1-261-en.pdf