Myeloid-derived suppressor cell-derived osteoclasts with bone resorption capacity in the joints of arthritic SKG mice

Myeloid-derived suppressor cell-derived osteoclasts with bone resorption capacity in the joints of arthritic SKG mice

BackgroundMyeloid-derived suppressor cells (MDSCs) are heterogeneous immature myeloid cells with immunosuppressive functions. It is known that MDSCs are expanded at inflammatory sites after migrating from bone marrow (BM) or spleen (Sp). In chronic inflammatory diseases such as rheumatoid arthritis...

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Bibliographic Details
Main Authors: Yoshikazu Fujikawa, Sho Sendo, Alfonso del Peral Fanjul, Hirotaka Yamada, Kenichi Uto, Yuzuru Yamamoto, Takumi Nagamoto, Akio Morinobu, Jun Saegusa
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-03-01
Series:Frontiers in Immunology
Subjects:
MDSCs
SKG mice
osteoclastogenesis
arthritis
microarray
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1168323/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2024.1168323/full

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