Global pathogenomic analysis identifies known and candidate genetic antimicrobial resistance determinants in twelve species

Abstract Surveillance programs for managing antimicrobial resistance (AMR) have yielded thousands of genomes suited for data-driven mechanism discovery. We present a workflow integrating pangenomics, gene annotation, and machine learning to identify AMR genes at scale. When applied to 12 species, 27...

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Bibliographic Details
Main Authors: Jason C. Hyun, Jonathan M. Monk, Richard Szubin, Ying Hefner, Bernhard O. Palsson
Format: Article
Language:English
Published: Nature Portfolio 2023-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-43549-9