Roles of dynein and dynactin in early endosome dynamics revealed using automated tracking and global analysis.

Microtubule-dependent movement is crucial for the spatial organization of endosomes in most eukaryotes, but as yet there has been no systematic analysis of how a particular microtubule motor contributes to early endosome dynamics. Here we tracked early endosomes labeled with GFP-Rab5 on the nanomete...

Full description

Bibliographic Details
Main Authors: Neftali Flores-Rodriguez, Salman S Rogers, David A Kenwright, Thomas A Waigh, Philip G Woodman, Victoria J Allan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3167862?pdf=render