Roles of dynein and dynactin in early endosome dynamics revealed using automated tracking and global analysis.
Microtubule-dependent movement is crucial for the spatial organization of endosomes in most eukaryotes, but as yet there has been no systematic analysis of how a particular microtubule motor contributes to early endosome dynamics. Here we tracked early endosomes labeled with GFP-Rab5 on the nanomete...
Main Authors: | Neftali Flores-Rodriguez, Salman S Rogers, David A Kenwright, Thomas A Waigh, Philip G Woodman, Victoria J Allan |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2011-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3167862?pdf=render |
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