Interferon Alpha Induces Cellular Autophagy and Modulates Hepatitis B Virus Replication

Interferon Alpha Induces Cellular Autophagy and Modulates Hepatitis B Virus Replication

Hepatitis B virus (HBV) infection causes acute and chronic liver diseases, including severe hepatitis, liver cirrhosis, and hepatocellular carcinoma (HCC). Interferon alpha 2a (IFNα-2a) is commonly used for treating chronic HBV infection. However, its efficacy remains relatively low. Yet, the immuno...

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Bibliographic Details
Main Authors: Jia Li, Thekla Kemper, Ruth Broering, Jieliang Chen, Zhenghong Yuan, Xueyu Wang, Mengji Lu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-02-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Hepatitis B virus
IFNα-2a
Akt/mTOR signaling
AMPK
autophagy
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2022.804011/full

Internet

https://www.frontiersin.org/articles/10.3389/fcimb.2022.804011/full

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