Could the Change of Excipient Content Improve the Stability of Gastroresistant Omeprazole Pellets?

Abstract Omeprazole (OM), a temperature, pH, and moisture-sensitive drug, poses formulation challenges. This study delves into the complex development of OM pellets, focusing on the impact of buffering excipients on stability and release. Addressing the challenges of OM pellet stability requires a c...

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Bibliographic Details
Main Authors: Priscila Chiamulera Mantovani, Fernanda Belincanta Borghi-Pangoni, Monica Villa Nova, Vanderson Galan, Henrique dos Santos, Francielle Sato, Marcos Luciano Bruschi, Andréa Diniz
Format: Article
Language:English
Published: Instituto de Tecnologia do Paraná (Tecpar) 2024-08-01
Series:Brazilian Archives of Biology and Technology
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132024000100624&lng=en&tlng=en