Neutrophil membrane-derived nanoparticle loading TLR7 agonists augments radiotherapy efficacy and boosts abscopal effect via regulating tumor microenvironment

Abstract Background Increasing evidence indicates that radiotherapy (RT) has synergistic inhibitory efficiency with immunotherapy agents in multiple cancers and enhances abscopal effects by regulating the innate immune response, which was further investigated in this study. Neutrophils are recruited...

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Bibliographic Details
Main Authors: Dehua Lu, Yanming Xu, Xiaodong Yang, Ying Li, Mengqing Li, Yuanyuan Zheng, Yuenan Wang, Weihu Wang, Shubin Wang, Jing Gao, Yajie Liu
Format: Article
Language:English
Published: BMC 2023-04-01
Series:Cancer Nanotechnology
Subjects:
Online Access:https://doi.org/10.1186/s12645-023-00193-8