SnapHiC2: A computationally efficient loop caller for single cell Hi-C data

SnapHiC2: A computationally efficient loop caller for single cell Hi-C data

Single cell Hi-C (scHi-C) technologies enable the study of chromatin spatial organization directly from complex tissues at single cell resolution. However, the identification of chromatin loops from single cells is challenging, largely due to the extremely sparse data. Our recently developed SnapHiC...

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Bibliographic Details
Main Authors: Xiaoqi Li, Lindsay Lee, Armen Abnousi, Miao Yu, Weifang Liu, Le Huang, Yun Li, Ming Hu
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:Computational and Structural Biotechnology Journal
Subjects:
Chromatin spatial organization
single cell Hi-C
Chromatin loops
the random walk with restart (RWR) algorithm
Online Access:http://www.sciencedirect.com/science/article/pii/S2001037022002021

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http://www.sciencedirect.com/science/article/pii/S2001037022002021

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