Tumorigenic effects of human mesenchymal stromal cells and fibroblasts on bladder cancer cells

Tumorigenic effects of human mesenchymal stromal cells and fibroblasts on bladder cancer cells

BackgroundPatients with muscle-invasive bladder cancer face a poor prognosis due to rapid disease progression and chemoresistance. Thus, there is an urgent need for a new therapeutic treatment. The tumor microenvironment (TME) has crucial roles in tumor development, growth, progression, and therapy...

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Bibliographic Details
Main Authors: Lucie M. Frerichs, Bastian Frerichs, Patrick Petzsch, Karl Köhrer, Joachim Windolf, Bernd Bittersohl, Michèle J. Hoffmann, Vera Grotheer
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-09-01
Series:Frontiers in Oncology
Subjects:
tumor microenvironment
bladder cancer
mesenchymal stem cells
fibroblasts
cisplatin resistance
CD44
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2023.1228185/full

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https://www.frontiersin.org/articles/10.3389/fonc.2023.1228185/full

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