Analysis of k-ras nuclear expression in fibroblasts and mesangial cells.

BACKGROUND: Ras GTPases are considered cytoplasmic proteins that must be localized to cell membranes for activation, and there are few evidences of the presence of any Ras isoform in nuclei of eukaryotic cells. METHODOLOGY/PRINCIPAL FINDINGS: Using conventional antibodies and inmunocytochemistry, di...

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Bibliographic Details
Main Authors: Isabel Fuentes-Calvo, Ana M Blázquez-Medela, Eugenio Santos, José M López-Novoa, Carlos Martínez-Salgado
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2806826?pdf=render