Illuminating the Sites of Enterovirus Replication in Living Cells by Using a Split-GFP-Tagged Viral Protein

ABSTRACT Like all other positive-strand RNA viruses, enteroviruses generate new organelles (replication organelles [ROs]) with a unique protein and lipid composition on which they multiply their viral genome. Suitable tools for live-cell imaging of enterovirus ROs are currently unavailable, as recom...

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Bibliographic Details
Main Authors: H. M. van der Schaar, C. E. Melia, J. A. C. van Bruggen, J. R. P. M. Strating, M. E. D. van Geenen, A. J. Koster, M. Bárcena, F. J. M. van Kuppeveld
Format: Article
Language:English
Published: American Society for Microbiology 2016-08-01
Series:mSphere
Subjects:
Online Access:https://journals.asm.org/doi/10.1128/mSphere.00104-16