Biliverdin regulates NR2E3 and zebrafish retinal photoreceptor development

Abstract NR2E3 is an orphan nuclear receptor whose loss-of-function causes abnormal retinal photoreceptor development and degeneration. However, despite that many nuclear receptors are regulated by binding of small molecule ligands, biological small molecule ligands regulating NR2E3 have not been id...

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Bibliographic Details
Main Authors: Blaine Connor, Kayla Titialii-Torres, Abigail E. Rockenhaus, Samuel Passamonte, Ann C. Morris, Young-Sam Lee
Format: Article
Language:English
Published: Nature Portfolio 2022-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-11502-3