Trefoil factor 3 promotes pancreatic carcinoma progression via WNT pathway activation mediated by enhanced WNT ligand expression

Abstract Pancreatic ductal adenocarcinoma (PDAC) is a major cause of cancer-related mortality with a dismal prognosis that has changed little over the past few decades. Further understanding of the molecular pathology of PDAC progression is urgently required in order to improve the prognosis of pati...

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Bibliographic Details
Main Authors: Feifei Cheng, Xuejuan Wang, Yi-Shiou Chiou, Chuyu He, Hui Guo, Yan Qin Tan, Basappa Basappa, Tao Zhu, Vijay Pandey, Peter E. Lobie
Format: Article
Language:English
Published: Nature Publishing Group 2022-03-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-022-04700-4