Knockout of immunotherapy prognostic marker genes eliminates the effect of the anti-PD-1 treatment
Abstract The efficacy of immunotherapy is largely patient-specific due to heterogeneity in tumors. Combining statistic power from a variety of immunotherapies across cancer types, we found four biological pathways significantly correlated with patient survival following immunotherapy. The expression...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2021-05-01
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Series: | npj Precision Oncology |
Online Access: | https://doi.org/10.1038/s41698-021-00175-2 |