HepaClear, a blood-based panel combining novel methylated CpG sites and protein markers, for the detection of early-stage hepatocellular carcinoma

HepaClear, a blood-based panel combining novel methylated CpG sites and protein markers, for the detection of early-stage hepatocellular carcinoma

Abstract Background Early screening and detection of hepatocellular carcinoma (HCC) can efficiently improve patient prognosis. We aimed to identify a series of hypermethylated DNA markers and develop a blood-based HCC diagnosis panel containing DNA methylation sites and protein markers with improved...

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Bibliographic Details
Main Authors: Yi Bai, Juan Xu, Deqiang Li, Xiaoyu Zhang, Dapeng Chen, Fucun Xie, Longmei Huang, Xiaotian Yu, Haitao Zhao, Yamin Zhang
Format: Article
Language:English
Published: BMC 2023-06-01
Series:Clinical Epigenetics
Subjects:
DNA methylation
Hepatocellular carcinoma
850K methylation array
Multi-target panel
Early detection
Online Access:https://doi.org/10.1186/s13148-023-01508-7

Internet

https://doi.org/10.1186/s13148-023-01508-7

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