Statistical integration of multi-omics and drug screening data from cell lines.

Data integration methods are used to obtain a unified summary of multiple datasets. For multi-modal data, we propose a computational workflow to jointly analyze datasets from cell lines. The workflow comprises a novel probabilistic data integration method, named POPLS-DA, for multi-omics data. The w...

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Bibliographic Details
Main Authors: Said El Bouhaddani, Matthias Höllerhage, Hae-Won Uh, Claudia Moebius, Marc Bickle, Günter Höglinger, Jeanine Houwing-Duistermaat
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-01-01
Series:PLoS Computational Biology
Online Access:https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1011809&type=printable