Statistical integration of multi-omics and drug screening data from cell lines.
Data integration methods are used to obtain a unified summary of multiple datasets. For multi-modal data, we propose a computational workflow to jointly analyze datasets from cell lines. The workflow comprises a novel probabilistic data integration method, named POPLS-DA, for multi-omics data. The w...
Main Authors: | Said El Bouhaddani, Matthias Höllerhage, Hae-Won Uh, Claudia Moebius, Marc Bickle, Günter Höglinger, Jeanine Houwing-Duistermaat |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2024-01-01
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Series: | PLoS Computational Biology |
Online Access: | https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1011809&type=printable |
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