RIG-I-Like Receptor-Mediated Recognition of Viral Genomic RNA of Severe Acute Respiratory Syndrome Coronavirus-2 and Viral Escape From the Host Innate Immune Responses

RIG-I-Like Receptor-Mediated Recognition of Viral Genomic RNA of Severe Acute Respiratory Syndrome Coronavirus-2 and Viral Escape From the Host Innate Immune Responses

RIG-I-like receptors (RLR), RIG-I and MDA5, are cytoplasmic viral RNA sensors that recognize viral double-stranded RNAs and trigger signals to induce antiviral responses, including type I interferon production. Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) caused the coronavirus disea...

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Bibliographic Details
Main Authors: Takahisa Kouwaki, Tasuku Nishimura, Guanming Wang, Hiroyuki Oshiumi
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Immunology
Subjects:
Innate immunity
Type I interferon
RIG-I
MDA5
SARS-CoV-2
coronavirus
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.700926/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2021.700926/full

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