Changes in function but not oligomeric size are associated with αB-crystallin lysine substitution

αB-Crystallin, ubiquitously expressed in many tissues including the ocular lens, is a small heat shock protein that can prevent protein aggregation. A number of post-translation modifications are reported to modify αB-crystallin function. Recent studies have identified αB-crystallin lysine residues...

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Bibliographic Details
Main Authors: Steven Droho, Mitchell E. Keener, Niklaus H. Mueller
Format: Article
Language:English
Published: Elsevier 2018-07-01
Series:Biochemistry and Biophysics Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2405580817302005