The effect of adding curcumin to sodium valproate in treatment of patients with bipolar disorder in the acute phase of mania: A randomized double-blind clinical trial

BackgroundInflammatory processes play a role in the etiopathogenesis of bipolar disorder type 1. Full therapeutic responses are seldom seen and the ongoing inflammatory processes in the brain could lead to neuronal loss. Curcumin, a relatively safe herbal compound, has been shown to have anti-inflam...

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Main Authors: Farzad Akbarzadeh, Nabahat Niksun, Ghazal Behravan, Fatemeh Behdani, Amir Hooshang Mohammadpour, Mahmoudreza Jaafari, Tayebeh Hosseini, Zahra Rajai, Alireza Ebrahimi, Mahboubeh Eslamzadeh
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Psychiatry
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Online Access:https://www.frontiersin.org/articles/10.3389/fpsyt.2023.1068277/full