Genome-scale modeling predicts metabolic differences between macrophage subtypes in colorectal cancer

Summary: Colorectal cancer (CRC) shows high incidence and mortality, partly due to the tumor microenvironment (TME), which is viewed as an active promoter of disease progression. Macrophages are among the most abundant cells in the TME. These immune cells are generally categorized as M1, with inflam...

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Bibliographic Details
Main Authors: Patrick E. Gelbach, Stacey D. Finley
Format: Article
Language:English
Published: Elsevier 2023-09-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223016462