Epigenetic impacts of ascorbate on human metastatic melanoma cells

Epigenetic impacts of ascorbate on human metastatic melanoma cells

In recent years, increasing evidence has emerged demonstrating that high-dose ascorbate bears cytotoxic effects on cancer cells in vitro and in vivo, making ascorbate a pro-oxidative drug that catalyzes hydrogen peroxide production in tissues instead of acting as a radical scavenger. This anticancer...

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Bibliographic Details
Main Authors: Sascha eVenturelli, Tobias W. Sinnberg, Alexander C. Berger, Seema eNoor, Mitchell Paul Levesque, Alexander eBöcker, Heike eNiessner, Ulrich eLauer, Michael eBitzer, Claus eGarbe, Christian eBusch
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-08-01
Series:Frontiers in Oncology
Subjects:
Melanoma
Cancer
epigenetics
microRNA
vitamin C
HDAC
Online Access:http://journal.frontiersin.org/Journal/10.3389/fonc.2014.00227/full

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http://journal.frontiersin.org/Journal/10.3389/fonc.2014.00227/full

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