Autogenic splenic implantation versus splenectomy in patients undergoing distal pancreatectomy for benign or low-grade malignant lesions of the distal pancreas: study protocol for a multicentre, open-label, randomized controlled trial (RESTORE)

Autogenic splenic implantation versus splenectomy in patients undergoing distal pancreatectomy for benign or low-grade malignant lesions of the distal pancreas: study protocol for a multicentre, open-label, randomized controlled trial (RESTORE)

Abstract Background The spleen plays a significant role in the clearance of circulating microorganisms. Sequelae of splenectomy, especially immunodeficiency, can have a deleterious effect on a patient’s health and even lead to death. Hence, splenectomy should be avoided and spleen preservation durin...

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Bibliographic Details
Main Authors: Mohammed Abu Hilal, Christoph Kuemmerli, Jasper P. Sijberden, Alma Moekotte, Giuseppe Zimmitti, Adnan Alseidi, Horacio J. Asbun, Ravi Marudanayagam, Morgan Bonds, Filipe Kunzler, Robert Sutcliffe, Efrem Eren, John N. Primrose, Anthony P. Williams
Format: Article
Language:English
Published: BMC 2024-01-01
Series:Trials
Subjects:
Splenectomy
Distal pancreatectomy
Overwhelming post-splenectomy infection syndrome
Autogenic splenic implantation
Online Access:https://doi.org/10.1186/s13063-023-07714-1

Internet

https://doi.org/10.1186/s13063-023-07714-1

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