Identification of Important N-Linked Glycosylation Sites in the Hemagglutinin Protein and Their Functional Impact on DC-SIGN Mediated Avian Influenza H5N1 Infection

Identification of Important N-Linked Glycosylation Sites in the Hemagglutinin Protein and Their Functional Impact on DC-SIGN Mediated Avian Influenza H5N1 Infection

DC-SIGN, a C-type lectin mainly expressed in dendritic cells (DCs), has been reported to mediate several viral infections. We previously reported that DC-SIGN mediated H5N1 influenza A virus (AIVs) infection, however, the important DC-SIGN interaction with N-glycosylation sites remain unknown. This...

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Bibliographic Details
Main Authors: Zih-Syuan Yang, Szu-Wei Huang, Wen-Hung Wang, Chih-Yen Lin, Chu-Feng Wang, Aspiro Nayim Urbina, Arunee Thitithanyanont, Sung-Pin Tseng, Po-Liang Lu, Yen-Hsu Chen, Sheng-Fan Wang
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:International Journal of Molecular Sciences
Subjects:
DC-SIGN
H5N1
N27Q
N39Q
hemagglutinin
N-linked glycosylation
Online Access:https://www.mdpi.com/1422-0067/22/2/743

Internet

https://www.mdpi.com/1422-0067/22/2/743

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