Combined TLR2 and TLR4 ligation in the context of bacterial or helminth extracts in human monocyte derived dendritic cells: molecular correlates for Th1/Th2 polarization

<p>Abstract</p> <p>Background</p> <p>Recognition of pathogens by dendritic cells (DCs) through interaction with pattern recognition receptors, including Toll like receptors (TLR), is crucial for the initiation of appropriate polarized T helper (Th) cell responses. Yet,...

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Bibliographic Details
Main Authors: van Hellemond Jaap J, Phylipsen Marion, Retra Kim, Everts Bart, van Riet Elly, Tielens Aloysius GM, van der Kleij Desiree, Hartgers Franca C, Yazdanbakhsh Maria
Format: Article
Language:English
Published: BMC 2009-02-01
Series:BMC Immunology
Online Access:http://www.biomedcentral.com/1471-2172/10/9