E47 as a novel glucocorticoid-dependent gene mediating lipid metabolism in patients with endogenous glucocorticoid excess

E47 as a novel glucocorticoid-dependent gene mediating lipid metabolism in patients with endogenous glucocorticoid excess

PurposeE47 has been identified as a modulating transcription factor of glucocorticoid receptor target genes, its loss protecting mice from metabolic adverse effects of glucocorticoids. We aimed to analyze the role of E47 in patients with endogenous glucocorticoid excess [Cushing’s syndrome (CS)] and...

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Bibliographic Details
Main Authors: Wei Zhang, Hanna Nowotny, Marily Theodoropoulou, Julia Simon, Charlotte M. Hemmer, Martin Bidlingmaier, Matthias K. Auer, Martin Reincke, Henriette Uhlenhaut, Nicole Reisch
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-11-01
Series:Frontiers in Endocrinology
Subjects:
Cushing’s syndrome
Cushing’s disease
transcription factor 3
comorbidity
dyslipidemia
ACTH
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2023.1249863/full

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https://www.frontiersin.org/articles/10.3389/fendo.2023.1249863/full

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