Environmental enrichment, age and PPARα interact to regulate proliferation in neurogenic niches

Environmental enrichment, age and PPARα interact to regulate proliferation in neurogenic niches

Peroxisome proliferator-activated receptor alpha (PPARα) ligands have been shown to modulate recovery after brain insults such as ischemia and irradiation by enhancing neurogenesis. In the present study, we investigated the effect of the genetic deletion of PPARα receptors on the proliferative rate...

Full description

Bibliographic Details
Main Authors: Margarita ePerez-Martin, Patricia eRivera, Eduardo eBlanco, Clara eLorefice, Juan eDecara, FRANCISCO JAVIER ePAVON, Antonia eSerrano, FERNANDO eRODRIGUEZ DE FONSECA, JUAN eSUAREZ
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-03-01
Series:Frontiers in Neuroscience
Subjects:
Aging
Hippocampus
Neurogenesis
environment
Subventricular zone
PPARα
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnins.2016.00089/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnins.2016.00089/full

Similar Items