Characterisation of innate fungal recognition in the lung.

The innate recognition of fungi by leukocytes is mediated by pattern recognition receptors (PRR), such as Dectin-1, and is thought to occur at the cell surface triggering intracellular signalling cascades which lead to the induction of protective host responses. In the lung, this recognition is aide...

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Bibliographic Details
Main Authors: Inês Faro-Trindade, Janet A Willment, Ann M Kerrigan, Pierre Redelinghuys, Sabelo Hadebe, Delyth M Reid, Naren Srinivasan, Helen Wainwright, Dirk M Lang, Chad Steele, Gordon D Brown
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3334970?pdf=render