PHLDA1 Suppresses TLR4-Triggered Proinflammatory Cytokine Production by Interaction With Tollip

Pleckstrin homology-like domain, family A, member 1 (PHLDA1) has been reported to be expressed in many mammalian tissues and cells. However, the functions and exact mechanisms of PHLDA1 remain unclear. In this study, we found that PHLDA1 expression was significantly altered in macrophages after expo...

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Bibliographic Details
Main Authors: Hui Peng, Juping Wang, Xuhong Song, Jiangni Huang, Haoming Hua, Fanlu Wang, Ziyun Xu, Jing Ma, Jie Gao, Jing Zhao, Anna Nong, Dongyang Huang, Bin Liang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-02-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.731500/full