Cyclic Rhamnosylated Elongation Factor P Establishes Antibiotic Resistance in <named-content content-type="genus-species">Pseudomonas aeruginosa</named-content>

ABSTRACT Elongation factor P (EF-P) is a ubiquitous bacterial protein that is required for the synthesis of poly-proline motifs during translation. In Escherichia coli and Salmonella enterica, the posttranslational β-lysylation of Lys34 by the PoxA protein is critical for EF-P activity. PoxA is abse...

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Main Authors: Andrei Rajkovic, Sarah Erickson, Anne Witzky, Owen E. Branson, Jin Seo, Philip R. Gafken, Michael A. Frietas, Julian P. Whitelegge, Kym F. Faull, William Navarre, Andrew J. Darwin, Michael Ibba
Format: Article
Language:English
Published: American Society for Microbiology 2015-07-01
Series:mBio
Online Access:https://journals.asm.org/doi/10.1128/mBio.00823-15