Selection of a SARS-CoV-2 antibody quantification method and development of an antibody reference standard for ELISA to test immunoglobulin preparations

Selection of a SARS-CoV-2 antibody quantification method and development of an antibody reference standard for ELISA to test immunoglobulin preparations

The development of COVID-globulin, a COVID-19-specific human immunoglobulin preparation, involved choosing a method to quantify antibodies to SARS-CoV-2. Antibody titre determination by virus neutralisation (VN) is labour-intensive and unsuitable for large-scale application. To enable routine testin...

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Bibliographic Details
Main Authors: T. I. Smolyanova, A. M. Nikolaeva, T. V. Vyaznikova, A. V. Ivanov, O. V. Belyakova, E. I. Sakanyan
Format: Article
Language:Russian
Published: Ministry of Health of the Russian Federation. Federal State Budgetary Institution «Scientific Centre for Expert Evaluation of Medicinal Products» 2022-12-01
Series:Биопрепараты: Профилактика, диагностика, лечение
Subjects:
virus neutralisation test
elisa
reference standard
immunoglobulin
sars-cov-2 antibodies
Online Access:https://www.biopreparations.ru/jour/article/view/420

Internet

https://www.biopreparations.ru/jour/article/view/420

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