Differential Expression of MED12-Associated Coding RNA Transcripts in Uterine Leiomyomas

Differential Expression of MED12-Associated Coding RNA Transcripts in Uterine Leiomyomas

Recent studies have demonstrated that somatic MED12 mutations in exon 2 occur at a frequency of up to 80% and have a functional role in leiomyoma pathogenesis. The objective of this study was to elucidate the expression profile of coding RNA transcripts in leiomyomas, with and without these mutation...

Full description

Bibliographic Details
Main Authors: Tsai-Der Chuang, Jianjun Gao, Derek Quintanilla, Hayden McSwiggin, Drake Boos, Wei Yan, Omid Khorram
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:International Journal of Molecular Sciences
Subjects:
leiomyoma
fibroid
myometrium
MED12 mutation
next-generation RNA sequencing
Online Access:https://www.mdpi.com/1422-0067/24/4/3742

Internet

https://www.mdpi.com/1422-0067/24/4/3742

Similar Items