The Therapeutic Effect of ICAM-1-Overexpressing Mesenchymal Stem Cells on Acute Graft-Versus-Host Disease

The Therapeutic Effect of ICAM-1-Overexpressing Mesenchymal Stem Cells on Acute Graft-Versus-Host Disease

Background/Aims: Mesenchymal stem cells (MSCs) do not readily migrate to appropriate sites, and this creates a major obstacle for their use in the treatment of graft-versus-host disease (GVHD). Intercellular adhesion molecule-1 (ICAM-1) can guide the homing of various immune cells to the proper anat...

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Bibliographic Details
Main Authors: Bo Tang, Xue Li, Yuanlin Liu, Xiuhui Chen, Ximei Li, Yanan Chu, Heng Zhu, Weijiang Liu, Fenfen Xu, Fan Zhou, Yi Zhang
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2018-05-01
Series:Cellular Physiology and Biochemistry
Subjects:
Mesenchymal stem cells
Intercellular adhesion molecule-1
Graft-versus-host disease
Bone marrow transplantation
Murine GVHD model
Online Access:https://www.karger.com/Article/FullText/489689

Internet

https://www.karger.com/Article/FullText/489689

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