Multifactor Regulation of the MdtJI Polyamine Transporter in Shigella.

The polyamine profile of Shigella, the etiological agent of bacillary dysentery in humans, differs markedly from that of E. coli, its innocuous commensal ancestor. Pathoadaptive mutations such as the loss of cadaverine and the increase of spermidine favour the full expression of the virulent phenoty...

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Main Authors: Adriano Leuzzi, Maria Letizia Di Martino, Rosaria Campilongo, Maurizio Falconi, Marialuisa Barbagallo, Lucia Marcocci, Paola Pietrangeli, Mariassunta Casalino, Milena Grossi, Gioacchino Micheli, Bianca Colonna, Gianni Prosseda
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4636849?pdf=render