Different Effects of Human Umbilical Cord Mesenchymal Stem Cells on Glioblastoma Stem Cells by Direct Cell Interaction or Via Released Soluble Factors

Different Effects of Human Umbilical Cord Mesenchymal Stem Cells on Glioblastoma Stem Cells by Direct Cell Interaction or Via Released Soluble Factors

Glioblastoma (GBM), the most common primary brain tumor in adults, is an aggressive, fast-growing and highly vascularized tumor, characterized by extensive invasiveness and local recurrence. In GBM and other malignancies, cancer stem cells (CSCs) are believed to drive invasive tumor growth and recur...

Full description

Bibliographic Details
Main Authors: Adriana Bajetto, Alessandra Pattarozzi, Alessandro Corsaro, Federica Barbieri, Antonio Daga, Alessia Bosio, Monica Gatti, Valerio Pisaturo, Rodolfo Sirito, Tullio Florio
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-10-01
Series:Frontiers in Cellular Neuroscience
Subjects:
mesenchymal stem cell
cancer stem cell
glioblastoma
chemokine
CXCR2
spheroid
Online Access:http://journal.frontiersin.org/article/10.3389/fncel.2017.00312/full

Internet

http://journal.frontiersin.org/article/10.3389/fncel.2017.00312/full

Similar Items