Nascent polypeptide-Associated Complex and Signal Recognition Particle have cardiac-specific roles in heart development and remodeling.

Establishing a catalog of Congenital Heart Disease (CHD) genes and identifying functional networks would improve our understanding of its oligogenic underpinnings. Our studies identified protein biogenesis cofactors Nascent polypeptide-Associated Complex (NAC) and Signal-Recognition-Particle (SRP) a...

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Bibliographic Details
Main Authors: Analyne M Schroeder, Tanja Nielsen, Michaela Lynott, Georg Vogler, Alexandre R Colas, Rolf Bodmer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-10-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1010448