PRMT2 silencing regulates macrophage polarization through activation of STAT1 or inhibition of STAT6

Abstract Background Macrophages play significant roles in innate immune responses and are heterogeneous cells that can be polarized into M1 or M2 phenotypes. PRMT2 is one of the type I protein arginine methyltransferases involved in inflammation. However, the role of PRMT2 in M1/M2 macrophage polari...

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Bibliographic Details
Main Authors: Ting Liu, Yinjiao Li, Muqiu Xu, Hongjun Huang, Yan Luo
Format: Article
Language:English
Published: BMC 2024-01-01
Series:BMC Immunology
Subjects:
Online Access:https://doi.org/10.1186/s12865-023-00593-w