Evaluation of The Preventive Effects of Carvedilol on Trastuzumab-Induced Cardiotoxicity in Early-Stage and Locally Advanced HER2-Positive Breast Cancer Patients

Evaluation of The Preventive Effects of Carvedilol on Trastuzumab-Induced Cardiotoxicity in Early-Stage and Locally Advanced HER2-Positive Breast Cancer Patients

Background: Trastuzumab is an efficient monoclonal antibody used in the treatment of Her2-positive breast cancer. Despite its prominent effect on Her2-positive patients’ disease-free Survival. Trastuzumab-induced cardiotoxicity is still one of the main challenges.  Angiotensin-converting enzyme inhi...

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Bibliographic Details
Main Authors: Mohsen Esfandbod, Mina Naderi, Azadeh Sadat Naseri, Ayat Ahmadi, Mohammadtaghi Noroozi, Saeid Sadeghi Joni
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2021-10-01
Series:International Journal of Hematology-Oncology and Stem Cell Research
Subjects:
Trastuzumab-induced cardiotoxicity; Carvedilol; Human epidermal growth factor receptor-2 (HER-2); Ejection fraction; Pulmonary artery pressure
Online Access:https://ijhoscr.tums.ac.ir/index.php/ijhoscr/article/view/1346

Internet

https://ijhoscr.tums.ac.ir/index.php/ijhoscr/article/view/1346

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