AKT2 deficiency impairs formation of the BCR signalosome

AKT2 deficiency impairs formation of the BCR signalosome

Abstract Background AKT2 is one of the key molecules that involves in the insulin-induced signaling and the development of cancer. In B cells, the function of AKT2 is unclear. Methods In this study, we used AKT2 knockout mice model to study the role of AKT2 in BCR signaling and B cell differentiatio...

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Main Authors: Zuochen Du, Di Yang, Yongjie Zhang, Xingtian Xuan, Han Li, Leling Hu, Changshun Ruan, Liling Li, Anwei Chen, Liang Deng, Yan Chen, Jingwen Xie, Lisa S. Westerberg, Lu Huang, Chaohong Liu
Format: Article
Language:English
Published: BMC 2020-04-01
Series:Cell Communication and Signaling
Online Access:http://link.springer.com/article/10.1186/s12964-020-00534-9

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http://link.springer.com/article/10.1186/s12964-020-00534-9

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