Sevoflurane induces cognitive impairment in young mice via autophagy.

<h4>Background</h4>Anesthesia may induce neurotoxicity and neurocognitive impairment in young mice. However, the underlying mechanism remains largely to be determined. Meanwhile, autophagy is involved in brain development and contributes to neurodegenerative diseases. We, therefore, set...

Full description

Bibliographic Details
Main Authors: Xiaoning Wang, Yuanlin Dong, Yiying Zhang, Tianzuo Li, Zhongcong Xie
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0216372