Preparation of α-Bromoketones Involving the Reaction of Enol Triethyl Borates with N-Bromosuccinimide
The ketones (5α- and 5β-cholestan-3-one and (1S,7aS)-1-tert-butoxy-hexahydro-7a-methyl-1H-inden-5-one) were efficiently α-monobrominated by treatment of the corresponding enol triethyl borates with N-bromosuccinimide (NBS).
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| Format: | Article |
| Language: | English |
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Hindawi Limited
2013-01-01
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| Series: | Journal of Chemistry |
| Online Access: | http://dx.doi.org/10.1155/2013/294107 |