Proteomic and functional analyses of the periodic membrane skeleton in neurons

In neurons the membrane-associated periodic skeleton (MPS) consists of actin, spectrin, and associated molecules. Here the authors use proteomic analysis and super-resolution imaging to provide insight into the molecular composition and organization of the MPS, and its functions in axon-diameter reg...

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Bibliographic Details
Main Authors: Ruobo Zhou, Boran Han, Roberta Nowak, Yunzhe Lu, Evan Heller, Chenglong Xia, Athar H. Chishti, Velia M. Fowler, Xiaowei Zhuang
Format: Article
Language:English
Published: Nature Portfolio 2022-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-30720-x