MicroRNAs Regulate Sleep and Sleep Homeostasis in Drosophila

Summary: To discover microRNAs that regulate sleep, we performed a genetic screen using a library of miRNA sponge-expressing flies. We identified 25 miRNAs that regulate baseline sleep; 17 were sleep-promoting and 8 promoted wake. We identified one miRNA that is required for recovery sleep after dep...

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Bibliographic Details
Main Authors: Patricia R. Goodwin, Alice Meng, Jessie Moore, Michael Hobin, Tudor A. Fulga, David Van Vactor, Leslie C. Griffith
Format: Article
Language:English
Published: Elsevier 2018-06-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124718308593