The emerging role of BET inhibitors in breast cancer

The emerging role of BET inhibitors in breast cancer

Bromodomain and extraterminal domain (BET) proteins are epigenetic molecules that regulate the expression of multiple genes involved in carcinogenesis. Breast cancer is an heterogenous disease emerging from aberrant gene expression and epigenetic alteration patterns. Amplification or overexpression...

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Bibliographic Details
Main Authors: Angeliki Andrikopoulou, Michalis Liontos, Konstantinos Koutsoukos, Meletios-Athanasios Dimopoulos, Flora Zagouri
Format: Article
Language:English
Published: Elsevier 2020-10-01
Series:Breast
Subjects:
BET inhibitors
Bromodomains
Epigenetic agents
Triple negative
Breast cancer
Drug discovery
Online Access:http://www.sciencedirect.com/science/article/pii/S0960977620301582

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http://www.sciencedirect.com/science/article/pii/S0960977620301582

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