Proteomics Profiling to Distinguish DOCK8 Deficiency From Atopic Dermatitis

Proteomics Profiling to Distinguish DOCK8 Deficiency From Atopic Dermatitis

Dedicator of cytokinesis 8 deficiency is an autosomal recessive primary immune deficiency disease belonging to the group of hyperimmunoglobulinemia E syndrome (HIES). The clinical phenotype of dedicator of cytokinesis 8 (DOCK8) deficiency, characterized by allergic manifestations, increased infectio...

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Bibliographic Details
Main Authors: Minnie Jacob, Afshan Masood, Zakiya Shinwari, Mai Abdel Jabbar, Hamoud Al-Mousa, Rand Arnaout, Bandar AlSaud, Majed Dasouki, Ayodele A. Alaiya, Anas M. Abdel Rahman
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-11-01
Series:Frontiers in Allergy
Subjects:
atopic dermatitis
dedicator of cytokinesis (DOCK8)
hyper IgE syndrome (HIES)
label-free proteomics
biomarker
multiple reaction monitoring
Online Access:https://www.frontiersin.org/articles/10.3389/falgy.2021.774902/full

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https://www.frontiersin.org/articles/10.3389/falgy.2021.774902/full

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